Alcoholic Liver Disease And Immune Response
نویسندگان
چکیده
منابع مشابه
Alcoholic Liver Disease And Immune Response
The alcoholic liver disease (ALD) continues to be a major health problem worldwide with respect to both morbidity and mortality. It is usually an outcome of excessive alcohol consumptions but can be worse by poor diet and genetic factors. This review aims to update the recent conditions of the epidemiology, pathogenesis, immune response and therapies to ALD. The new insights into the pathogenes...
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Ethanol consumption is known to cause significant acute liver damage resulting in hepatic fibrosis and eventual cirrhosis when consumed chronically. The mechanism(s) by which ethanol exerts its damaging effects on the liver are not well understood; however, recent scientific investigation has begun to delineate the earliest events in alcoholic liver disease. From these studies, it is apparent t...
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Many types of innate (natural killer cells, natural killer T cells, and Kupffer cells/macrophages) and adaptive (T cells and B cells) immune cells are enriched within the liver and function in liver physiology and pathology. Liver pathology is generally induced by two types of immunologic insults: failure to eliminate antigens derived from the gastrointestinal tract which are important for host...
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Non-alcoholic fatty liver disease (NAFLD) is currently the most common liver disease worldwide, both in adults and children. It is characterized by an aberrant lipid storage in hepatocytes, named hepatic steatosis. Simple steatosis remains a benign process in most affected patients, while some of them develop superimposed necroinflammatory activity with a non-specific inflammatory infiltrate an...
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Background & Objective: Nonalcoholic fatty liver diseases (NAFLD) is the major cause of hepatocellular carcinoma and increases the risk of mortality. Understanding the trends of its clinical and biochemical changes is essential to identify patients with NAFLD that are at the greatest risk of nonalcoholic steatohepatitis (NASH) and cirrhosis in Iran. M...
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ژورنال
عنوان ژورنال: The Open Gastroenterology Journal
سال: 2012
ISSN: 1874-2599
DOI: 10.2174/1874259901206010008